Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | CCR3 | P51677 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462774 | 0.87 | S1PR1 (0.49) | DRD2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7461499 | 0.85 | CACNA1G (0.57) | — | |
| SCHEMBL7465032 | 0.83 | S1PR1 (0.48) | CYP3A4CYP2D6CYP2C19HDAC1 | |
| SCHEMBL7467430 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL7465897 | 0.78 | DRD2 (0.49) | DRD2 | |
| SCHEMBL7963986 | 0.75 | DRD2 (0.62) | DRD2PRCP | |
| SCHEMBL7474472 | 0.75 | S1PR1 (0.46) | DRD2 | |
| SCHEMBL6802419 | 0.74 | HTR7 (0.57) | DRD2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7476441 | 0.74 | LMNA (0.64) | DRD2 | |
| SCHEMBL11200638 | 0.73 | DRD2 (0.69) | DRD2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |