Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 10/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472177 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ESPL1EPAS1LMNAPOLB | |
| SCHEMBL358028 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL7045277 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL26688580 | 0.76 | PSIP1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8134166 | 0.75 | TXNRD1 (0.32) | POLB | |
| SCHEMBL3305889 | 0.75 | MAPT (0.49) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL7529213 | 0.73 | LMNA (0.47) | ALDH1A1ESPL1EPAS1RXFP1LMNA | |
| SCHEMBL28247559 | 0.71 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL8129522 | 0.71 | MMP13 (0.38) | KMT2A | |
| SCHEMBL9154 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-2576529-B1 | Heterocyclic alkanol derivatives as fungicides | BAYER IP GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |