Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471017 | 0.84 | MAPK1 (0.44) | NPC1RAB9AKDM4EALDH1A1RXFP1 | |
| SCHEMBL7469964 | 0.84 | NPC1 (0.42) | NPC1RAB9AKCNE1KCNQ1KDM4E | |
| SCHEMBL7470001 | 0.83 | KCNE1 (0.42) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL7464041 | 0.82 | SMN1; SMN2 (0.46) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL4623467 | 0.81 | TRPV1 (0.42) | TRPV1RAB9AKCNE1KCNQ1ALDH1A1 | |
| SCHEMBL7468807 | 0.80 | KCNE1 (0.40) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL7478341 | 0.80 | ALDH1A1 (0.48) | TRPV1KCNE1KCNQ1ALDH1A1CYP3A4 | |
| SCHEMBL7477267 | 0.80 | ALDH1A1 (0.43) | TRPV1NPC1RAB9AKCNE1KCNQ1 | |
| SCHEMBL7479262 | 0.79 | LMNA (0.41) | TRPV1RAB9AKCNE1KCNQ1KDM4E | |
| SCHEMBL7476073 | 0.79 | KCNE1 (0.40) | TRPV1KCNE1KCNQ1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905131-B1 | Sulfonamid-substituted chromans, process for their preparation, their use as medicine, and pharmaceutical preparation containing them | AVENTIS PHARMA GMBH (DE) | 2002-04-10 | — | — | EP | disclosed |