Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL7484090 | 0.95 | ALOX12 (0.38) | POLBTGFBR1ALOX12ALDH1A1PDE4B | |
| Ethane SCHEMBL7482421 | 0.94 | TGFBR1 (0.39) | POLBTGFBR1ALOX12HTR6PTGES | |
| Ethane SCHEMBL7482696 | 0.93 | ATIC (0.39) | POLBALOX12 | |
| SCHEMBL7441054 | 0.91 | ALOX12 (0.37) | POLBTGFBR1ALOX12HTR6PTGES | |
| Ethane SCHEMBL7485196 | 0.90 | HSP90AA1 (0.39) | ALDH1A1HPGDPDE4BMEN1KMT2A | |
| SCHEMBL9287557 | 0.86 | HTR6 (0.35) | POLBTGFBR1ALOX12HTR6PTGES | |
| SCHEMBL7450441 | 0.85 | ALOX12 (0.39) | ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL7441056 | 0.85 | ALDH1A1 (0.40) | POLBHTR6PTGESGAAALDH1A1 | |
| SCHEMBL7443310 | 0.84 | POLB (0.36) | POLBTGFBR1ALOX12HTR6PTGES | |
| SCHEMBL7432825 | 0.84 | NAMPT (0.38) | ALOX12GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |