Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL7480930 | 0.90 | POLB (0.39) | HPGDMEN1KMT2AALDH1A1PDE4B | |
| SCHEMBL7448162 | 0.90 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1HPGDHSD17B10MAPT | |
| SCHEMBL7443321 | 0.87 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1HPGDHSD17B10MAPT | |
| SCHEMBL7448164 | 0.87 | ALDH1A1 (0.40) | HSP90AA1HSP90AB1HPGDHSD17B10MAPT | |
| Ethane SCHEMBL7484090 | 0.86 | ALOX12 (0.38) | HSP90AA1HSP90AB1MAPTMEN1KMT2A | |
| SCHEMBL7448174 | 0.85 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1HPGDHSD17B10MAPT | |
| Ethane SCHEMBL7482421 | 0.84 | TGFBR1 (0.39) | MAPTTP53ALDH1A1LMNATDP1 | |
| Ethane SCHEMBL7482696 | 0.84 | ATIC (0.39) | AR | |
| SCHEMBL7441054 | 0.83 | ALOX12 (0.37) | ALDH1A1SMN1; SMN2HTTPDE4B | |
| SCHEMBL6175973 | 0.82 | HSD11B1 (0.39) | HSP90AA1HSP90AB1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |