Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.90 | TP53 (0.39) | SRCPTGDR2GAASLC13A5SLC2A1 | |
| SCHEMBL749644 | 0.89 | TACR1 (0.39) | CETPSRCPTGDR2TACR1SLC13A5 | |
| SCHEMBL745530 | 0.89 | HDAC1 (0.41) | SRCPTGDR2SLC13A5 | |
| SCHEMBL748197 | 0.89 | SRC (0.36) | SRCPTGDR2SLC13A5 | |
| SCHEMBL747722 | 0.88 | ESRRG (0.41) | SRCSLC13A5 | |
| SCHEMBL749993 | 0.87 | LPAR1 (0.39) | SRCSLC13A5 | |
| SCHEMBL751065 | 0.87 | SRC (0.38) | SRCPTGDR2SLC13A5SLC2A1 | |
| SCHEMBL748116 | 0.87 | SRC (0.39) | SRCPTGDR2TACR1GAASLC13A5 | |
| SCHEMBL750133 | 0.87 | SRC (0.36) | SRCTACR1SLC13A5 | |
| SCHEMBL749647 | 0.87 | LMNA (0.39) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |