Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484149 | 0.84 | DDB1 (0.33) | HTR5ABLMHTTALDH1A1MAPT | |
| SCHEMBL7481509 | 0.83 | ALDH1A1 (0.44) | ACEMMP13HTR5AHTR1AHTR1D | |
| SCHEMBL7479816 | 0.78 | LMNA (0.47) | ACEMMP13TSHRCYP3A4LMNA | |
| SCHEMBL7836971 | 0.77 | CREBBP (0.46) | HTR5APYGLPYGMALDH1A1MAPT | |
| SCHEMBL7825601 | 0.76 | CMA1 (0.44) | HTR5AHTR3AHTTPYGLPYGM | |
| SCHEMBL17713701 | 0.75 | LMNA (0.42) | ACEMMP13HTR5AHTR1AHTR1D | |
| SCHEMBL7837367 | 0.73 | AHR (0.44) | HTR5AHTR1DHTR2AHTR2CHTR7 | |
| SCHEMBL7480378 | 0.71 | CASP3 (0.47) | TSHRCYP3A4PDE3BPDE3ABRD4 | |
| SCHEMBL7486170 | 0.68 | HTR5A (0.38) | HTR5APDE3BPDE3AHTTTGM2 | |
| SCHEMBL7826445 | 0.68 | CA9 (0.43) | HTR5AMEN1KMT2AMAPTDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |