Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960185 | 0.80 | LTB4R (0.49) | MPOLMNAGLAALDH1A1MAPT | |
| SCHEMBL28355292 | 0.73 | ALDH1A1 (0.50) | TDP1L3MBTL1LMNAGLAALDH1A1 | |
| SCHEMBL21974599 | 0.72 | L3MBTL1 (0.67) | MPOPBRM1ATMTDP1L3MBTL1 | |
| SCHEMBL2578134 | 0.72 | ALDH1A1 (0.46) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL23098254 | 0.72 | ATM (0.61) | MPOPBRM1ATMTDP1L3MBTL1 | |
| SCHEMBL7484753 | 0.71 | MPO (0.46) | MPOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15544824 | 0.71 | GAA (0.64) | MAPTMEN1KMT2A | |
| SCHEMBL2900640 | 0.70 | ATM (0.63) | PBRM1ATMTDP1L3MBTL1CYP19A1 | |
| SCHEMBL7491732 | 0.69 | MAPT (0.51) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL7487352 | 0.69 | PBRM1 (0.43) | MPOPBRM1ABL1FABP6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |