Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487346 | 0.71 | XDH (0.36) | CNR2 | |
| SCHEMBL3684740 | 0.71 | ATM (0.63) | PBRM1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL7491732 | 0.70 | MAPT (0.51) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL548283 | 0.70 | L3MBTL1 (0.61) | PBRM1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL2578134 | 0.70 | ALDH1A1 (0.46) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL10696587 | 0.69 | CYP1A2 (0.56) | PBRM1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL7487232 | 0.69 | MPO (0.55) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL15544824 | 0.69 | GAA (0.64) | MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7496076 | 0.69 | MAPT (0.50) | PBRM1ABL1FABP6ATMTDP1 | |
| SCHEMBL7488968 | 0.69 | ATM (0.59) | PBRM1ATMTDP1L3MBTL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |