Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867118 | 0.75 | LMNA (0.39) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL9296428 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL8313997 | 0.71 | MAPT (0.49) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL24631370 | 0.70 | ALOX5 (0.43) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL30134826 | 0.70 | ALOX5 (0.43) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL6611136 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL29617021 | 0.68 | TSHR (0.80) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL3683272 | 0.68 | TSHR (0.80) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL24631546 | 0.67 | TDP2 (0.40) | ALDH1A1TSHRMAPTGLAMEN1 | |
| SCHEMBL24631747 | 0.67 | LMNA (0.40) | ALDH1A1TSHRMAPTGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825189-B1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-01-02 | — | — | EP | disclosed |