Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943876 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL1004649 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL20938109 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL38654552 | 0.80 | MLYCD (0.53) | ALDH1A1HPGDSMN1; SMN2PLK1NOX1 | |
| SCHEMBL11437063 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2OPRD1LMNA | |
| SCHEMBL28029151 | 0.78 | HPGD (0.63) | ALDH1A1HPGDSMN1; SMN2OPRD1LMNA | |
| SCHEMBL751000 | 0.78 | OPRM1 (0.67) | ALDH1A1HPGDSMN1; SMN2PLK1OPRM1 | |
| SCHEMBL13615594 | 0.77 | OPRM1 (0.45) | ALDH1A1HPGDPLK1NOX1OPRM1 | |
| SCHEMBL5859663 | 0.77 | PLK1 (0.61) | ALDH1A1HPGDSMN1; SMN2PLK1HAO1 | |
| SCHEMBL6182687 | 0.77 | PLK1 (0.61) | ALDH1A1HPGDSMN1; SMN2PLK1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077120-B2 | Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto | EMORY UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200085837-A1 | Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto | UNIV EMORY (US) | 2020-03-19 | — | — | US | disclosed |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-07-13 | — | — | US | disclosed |
| US-8293436-B2 | Oxime derivative, photopolymerizable composition, color filter, and process for producing the same | FUJIFILM CORPORATION (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8293436-B2 | Oxime derivative, photopolymerizable composition, color filter, and process for producing the same | FUJIFILM CORPORATION (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8137890-B2 | Colored photosensitive composition, color filter, and method for manufacturing color filter | FUJIFILM CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8137890-B2 | Colored photosensitive composition, color filter, and method for manufacturing color filter | FUJIFILM CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20120037860-A1 | DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120037860-A1 | DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8057969-B2 | Dye-containing negative curable composition, color filter and method for producing the same | FUJIFILM CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20070212623-A1 | Dye-containing negative working curable composition, color filter and production method thereof | FUJIFILM CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070212623-A1 | Dye-containing negative working curable composition, color filter and production method thereof | FUJIFILM CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070203255-A1 | Oxime derivative, photopolymerizable composition, color filter, and process for producing the same | FUJIFILM CORPORATION (JP) | 2007-08-30 | — | — | US | disclosed |
| US-20070203255-A1 | Oxime derivative, photopolymerizable composition, color filter, and process for producing the same | FUJIFILM CORPORATION (JP) | 2007-08-30 | — | — | US | disclosed |
| US-20070190435-A1 | Dye-containing photosensitive composition, color filter using the same, and production method thereof | FUJIFILM CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070190435-A1 | Dye-containing photosensitive composition, color filter using the same, and production method thereof | FUJIFILM CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070099096-A1 | Dye-containing curable composition, color filter and method of producing thereof | FUJIFILM CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20070099096-A1 | Dye-containing curable composition, color filter and method of producing thereof | FUJIFILM CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077120-B2 | Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto | PTGER2, PTGES2, PTGES | ALDH1A1 1193/4885HPGD 197/4885SMN1; SMN2 3710/4885 |
| US-20200085837-A1 | Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto | PTGER2, PTGES2, PTGER1 | ALDH1A1 1095/4885HPGD 141/4885SMN1; SMN2 3187/4885 |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | ALDH1A1 3524/4885HPGD 1850/4885SMN1; SMN2 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.