Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517537 | 0.85 | KCNN2 (0.33) | MAOACTSSHTR1AHTR2AHTR7 | |
| SCHEMBL7827664 | 0.81 | ROCK2 (0.38) | MAOADRD3 | |
| SCHEMBL7510363 | 0.80 | CNR1 (0.41) | CTSS | |
| SCHEMBL7521473 | 0.79 | CNR1 (0.41) | — | |
| SCHEMBL7513395 | 0.79 | MAOA (0.39) | MAOAPLAUDRD3 | |
| SCHEMBL8308422 | 0.79 | ACHE (0.36) | PLAU | |
| SCHEMBL8310121 | 0.77 | ACHE (0.38) | PLAUCTSSKMT2A | |
| SCHEMBL7510864 | 0.77 | — | — | |
| SCHEMBL7824786 | 0.76 | DRD2 (0.37) | HTR1ADRD3MAPTHTTKMT2A | |
| SCHEMBL7512685 | 0.76 | BTK (0.38) | PLAUMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |