Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7641818 | 0.98 | NPC1 (0.48) | S1PR5MMP1ADAM17SPHK1NPC1 | |
| SCHEMBL7951375 | 0.90 | ADAM17 (0.59) | MMP1ADAM17MMP9MMP13 | |
| SCHEMBL7511232 | 0.89 | S1PR5 (0.48) | S1PR5MMP1ADAM17HTR2AFFAR2 | |
| SCHEMBL7555707 | 0.88 | ALDH1A1 (0.50) | MMP1ADAM17SMN1; SMN2HTR2AMMP9 | |
| SCHEMBL7510863 | 0.88 | POLB (0.54) | S1PR5MMP1ADAM17SPHK1NPC1 | |
| SCHEMBL7555310 | 0.87 | MMP8 (0.46) | S1PR5MMP1ADAM17SMN1; SMN2HTR2A | |
| SCHEMBL7550516 | 0.86 | S1PR5 (0.51) | S1PR5MMP1ADAM17RAB9ASMN1; SMN2 | |
| Hydroxyamine SCHEMBL7549789 | 0.85 | MMP8 (0.45) | S1PR5MMP1ADAM17SMN1; SMN2HTR2A | |
| SCHEMBL7506020 | 0.83 | S1PR5 (0.53) | S1PR5MMP1ADAM17SPHK1NPC1 | |
| SCHEMBL7548378 | 0.80 | MMP13 (0.46) | MMP1ADAM17MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247419-A | Paeoniflorin benzenesulfonate impurity and preparation method and application thereof | 广州白云山汉方现代药业有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247420-A | Paeoniflorin-6' -O-benzenesulfonate impurity, and preparation method and application thereof | 广州白云山汉方现代药业有限公司 | 2023-12-19 | — | — | CN | claimed |
| WO-2023000518-A1 | METHOD FOR SYNTHESIZING PAEONIFLORIN DERIVATIVE | 广州白云山汉方现代药业有限公司 | 2023-01-26 | — | — | WO | claimed |
| CN-117247420-A | Paeoniflorin-6' -O-benzenesulfonate impurity, and preparation method and application thereof | 广州白云山汉方现代药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247419-A | Paeoniflorin benzenesulfonate impurity and preparation method and application thereof | 广州白云山汉方现代药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-102516289-B | Preparation method of sulfur bridge-containing reverse ester thiol methyltin | Hubei nanxing chemical general factory | 2015-07-15 | — | — | CN | disclosed |
| CN-102516289-A | Preparation method of sulfur bridge-containing reverse ester thiol methyltin | Hubei nanxing chemical general factory | 2012-06-27 | — | — | CN | disclosed |
| US-6441023-B1 | FOR THERAPY OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN HOME PRODUCTS CORPORATION | 2002-08-27 | — | — | US | disclosed |
| US-20020032186-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-03-14 | — | — | US | disclosed |
| JP-2002003812-A | TWO-PACK TYPE URETHANE ADHESIVE AND METHOD FOR MANUFACTURING SANDWICHED HONEYCOMB STRUCTURE PANEL USING THE SAME | SEKISUI CHEM CO LTD | 2002-01-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032186-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | S1PR5 1323/4885MMP1 4/4885ADAM17 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.