SCHEMBL751999

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754229	0.90	KDM4E (0.39)	IDH1GRM5KDM5AKDM4CACACB
	SCHEMBL755667	0.86	ALKBH1 (0.43)	ALKBH1PKMGRM5KDM5AKDM4C
	SCHEMBL756685	0.82	P2RX3 (0.38)	IDH1GRM5KDM5AKDM4CP2RX3
	SCHEMBL752783	0.79	ACACB (0.38)	PKMGRM5TRPV3PTGER1MCHR1
	SCHEMBL756359	0.75	LIPG (0.43)	ALKBH1GRM5KDM5AKDM4CMCHR1
	SCHEMBL755270	0.71	HRH3 (0.38)	ALKBH1IDH1GRM5ACACB
	SCHEMBL2488805	0.69	ALKBH1 (0.42)	ALKBH1PKMGRM5TRPV3PTGER1
	SCHEMBL754532	0.69	JAK2 (0.43)	GRM5MCHR1ACACB
	SCHEMBL7464319	0.68	PDE5A (0.50)	ALKBH1PKMGRM5
	SCHEMBL752035	0.67	BACE1 (0.39)	IDH1GRM5P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.