Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526697 | 0.86 | — | — | |
| SCHEMBL7517211 | 0.85 | ALOX5 (0.33) | — | |
| SCHEMBL7526911 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL7525678 | 0.79 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL8442028 | 0.78 | GABRA1 (0.36) | GABRA1GABRB2KMT2A | |
| SCHEMBL7520240 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2MEN1NPC1KMT2A | |
| SCHEMBL7520622 | 0.75 | FAAH (0.34) | GABRA1GABRB2MEN1NPC1KMT2A | |
| SCHEMBL7521936 | 0.74 | ALDH1A1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL7517853 | 0.70 | SHBG (0.36) | GABRA1GABRB2 | |
| SCHEMBL7521149 | 0.69 | HSP90AA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |