Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 10/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | GAK | O14976 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799220 | 0.90 | ABCG2 (0.65) | ABCG2EGFRERBB2BRAFKDR | |
| SCHEMBL30968993 | 0.80 | EGFR (0.53) | EGFRERBB2BRAFKDRFBP1 | |
| SCHEMBL5909044 | 0.79 | FBP1 (0.58) | ABCG2EGFRERBB2BRAFKDR | |
| SCHEMBL7753469 | 0.79 | FGFR1 (0.56) | ABCG2EGFRERBB2BRAFKDR | |
| SCHEMBL4233633 | 0.77 | KDR (0.81) | ABCG2EGFRERBB2KDRGAK | |
| SCHEMBL7757002 | 0.77 | PDGFRB (0.59) | EGFRBRAFKDRKDM4ECDK1 | |
| SCHEMBL28221880 | 0.76 | PDGFRB (0.64) | ABCG2EGFRERBB2BRAFFBP1 | |
| SCHEMBL7800405 | 0.76 | EGFR (0.56) | ABCG2EGFRERBB2FBP1KDM4E | |
| SCHEMBL8812882 | 0.75 | PDGFRB (0.57) | EGFRBRAFKDRKDM4ECDK1 | |
| SCHEMBL1246693 | 0.74 | ABCG2 (0.58) | ABCG2EGFRERBB2BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177601-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177601-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | PKD1, REN, BDKRB1 | ABCG2 398/4885EGFR 1367/4885ERBB2 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.