Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926760 | 0.83 | RAB9A (0.40) | MEN1KMT2AALDH1A1RAPGEF4 | |
| SCHEMBL28463421 | 0.83 | RAB9A (0.40) | MEN1KMT2AALDH1A1RAPGEF4 | |
| SCHEMBL7524238 | 0.79 | RAPGEF4 (0.46) | MEN1KMT2AALDH1A1RAPGEF4 | |
| SCHEMBL7524044 | 0.77 | KIF11 (0.40) | MEN1KMT2A | |
| SCHEMBL7517906 | 0.77 | KMT2A (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7519427 | 0.76 | GRM4 (0.44) | GRM4MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL7520161 | 0.75 | KIF11 (0.52) | ALDH1A1RAPGEF4 | |
| SCHEMBL7517549 | 0.74 | P2RX3 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7522665 | 0.72 | CTRC (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7513779 | 0.70 | AHR (0.35) | KDRPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |