Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSF1 | Q00613 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528386 | 0.92 | MAPT (0.41) | HSF1POLBFAAHCES1CTSB | |
| SCHEMBL7533002 | 0.85 | FAAH (0.38) | HSF1FAAHCES1CTSSCTSK | |
| SCHEMBL7535944 | 0.84 | MAPT (0.42) | FAAHCES1CTSBCTSSCTSK | |
| SCHEMBL7535316 | 0.83 | CTSL (0.40) | POLBFAAHCES1CTSBCTSS | |
| SCHEMBL7536589 | 0.83 | SMN1; SMN2 (0.41) | LMNAHSF1POLBFAAHCES1 | |
| SCHEMBL7530295 | 0.83 | FAAH (0.35) | LMNAHSF1FAAHCES1CTSB | |
| SCHEMBL7529863 | 0.82 | TACR2 (0.38) | HSF1FAAHCES1CTSBCTSS | |
| SCHEMBL7531988 | 0.81 | SLC6A5 (0.42) | LMNAHPGD | |
| SCHEMBL7532248 | 0.81 | CTSL (0.47) | LMNACTSBCTSSCTSK | |
| SCHEMBL7531423 | 0.80 | CTSL (0.39) | POLBFAAHCES1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |