Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.48 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534822 | 0.91 | HTT (0.51) | MAPTMEN1KMT2AACLYRAB9A | |
| SCHEMBL7531850 | 0.90 | ACLY (0.46) | MAPTMEN1KMT2AKDM4EKCNH2 | |
| SCHEMBL7534348 | 0.90 | KDM4E (0.44) | SLC10A2SLC10A1SLC10A6MAPTTHRB | |
| SCHEMBL7531845 | 0.88 | HTT (0.47) | MAPTMEN1KMT2AACLYGRM4 | |
| SCHEMBL7530740 | 0.88 | MEN1 (0.50) | MAPTMEN1KMT2AKDM4EKCNH2 | |
| SCHEMBL7537270 | 0.87 | ITGA1 (0.47) | MAPTTHRBMEN1KMT2AKDM4E | |
| SCHEMBL7537394 | 0.86 | SLC10A2 (0.53) | SLC10A2SLC10A1SLC10A6MAPTTHRB | |
| SCHEMBL7533627 | 0.85 | P2RX1 (0.45) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL7538739 | 0.85 | MEN1 (0.49) | SLC10A2SLC10A1SLC10A6MAPTTHRB | |
| SCHEMBL7537385 | 0.85 | ACLY (0.51) | SLC10A2SLC10A1SLC10A6MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |