Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531372 | 0.87 | SLC10A2 (0.48) | MAPTTHRBALDH1A1MEN1KMT2A | |
| SCHEMBL7534822 | 0.86 | HTT (0.51) | LMNAMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL7537204 | 0.84 | MAPT (0.51) | MAPTNPC1ALDH1A1TP53BDKRB1 | |
| SCHEMBL7537338 | 0.82 | MAPT (0.49) | LMNAMAPTALDH1A1TP53MEN1 | |
| SCHEMBL7531845 | 0.82 | HTT (0.47) | LMNAMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL7531850 | 0.81 | ACLY (0.46) | LMNAMAPTNPC1ALDH1A1NPSR1 | |
| SCHEMBL7530740 | 0.81 | MEN1 (0.50) | LMNAMAPTALDH1A1BDKRB1MEN1 | |
| SCHEMBL7533627 | 0.81 | P2RX1 (0.45) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL7537211 | 0.81 | KMT2A (0.55) | SENP7CASP3SENP8SENP6ALDH1A1 | |
| SCHEMBL7537385 | 0.81 | ACLY (0.51) | LMNAMAPTALDH1A1TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |