Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533627 | 0.96 | P2RX1 (0.45) | KDM4EMEN1KMT2AKCNH2GAA | |
| SCHEMBL7531372 | 0.90 | SLC10A2 (0.48) | KDM4EMEN1PKMKMT2AKCNH2 | |
| SCHEMBL7535071 | 0.86 | LMNA (0.47) | KDM4EMEN1KMT2AKCNH2NPC1 | |
| SCHEMBL7532549 | 0.85 | KAT6A (0.50) | MEN1KMT2AGAAP2RX1NPC1 | |
| SCHEMBL7534822 | 0.81 | HTT (0.51) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL7531845 | 0.81 | HTT (0.47) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL7532963 | 0.81 | CYP3A4 (0.49) | KDM4EMEN1KMT2AGAAP2RX1 | |
| SCHEMBL7531850 | 0.81 | ACLY (0.46) | KDM4EMEN1KMT2AKCNH2NPC1 | |
| SCHEMBL7530740 | 0.81 | MEN1 (0.50) | KDM4EMEN1KMT2AKCNH2MAPT | |
| SCHEMBL7537270 | 0.78 | ITGA1 (0.47) | KDM4EMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |