Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.44 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.44 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538051 | 0.88 | HTT (0.49) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7532778 | 0.87 | SLC20A2 (0.54) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7534376 | 0.85 | L3MBTL1 (0.52) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7532963 | 0.83 | CYP3A4 (0.49) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7533623 | 0.83 | ACLY (0.55) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7533934 | 0.83 | HTT (0.52) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7534822 | 0.82 | HTT (0.51) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7531893 | 0.81 | HTT (0.50) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7532028 | 0.81 | ADORA3 (0.53) | HTTMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7534436 | 0.81 | LMNA (0.60) | HTTMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |