Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737621 | 0.94 | CA1 (0.44) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL4889271 | 0.94 | OPRM1 (0.43) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL18488994 | 0.83 | OPRM1 (0.36) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL17263912 | 0.82 | CA2 (0.48) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL28409931 | 0.82 | TSHR (0.47) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL10437679 | 0.76 | CA2 (0.43) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL29815044 | 0.75 | TSHR (0.33) | LMNATSHR | |
| Potassium Ion SCHEMBL27585969 | 0.74 | OPRM1 (0.48) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL11523070 | 0.74 | ALDH1A1 (0.44) | OPRM1DNM1TSHRCA2 | |
| Potassium Ion SCHEMBL23850020 | 0.72 | OPRM1 (0.46) | OPRM1CA1LMNADNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077266-A1 | Portable stain removal product | THE PROCTER & GAMBLE COMPANY | 2002-06-20 | — | — | US | disclosed |
| WO-2002011604-A1 | A PORTABLE STAIN REMOVAL PRODUCT | THE PROCTER AND GAMBLE COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |