Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077887 | 0.87 | HSD11B1 (0.51) | CA1CA2MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL250324 | 0.82 | POLB (0.44) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL30859041 | 0.80 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8863056 | 0.80 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10919387 | 0.79 | HSD11B1 (0.54) | CA1CA2MMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL11261755 | 0.78 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL124382 | 0.78 | POLB (0.44) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29558643 | 0.78 | POLB (0.44) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20758153 | 0.77 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5082293 | 0.75 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115762-A1 | Polycarbonate resin composition containing titanium dioxide and sulfone sulfonate salt | CHEIL INDUSTRIES, INC. (KR) | 2002-08-22 | — | — | US | claimed |
| US-20020115762-A1 | Polycarbonate resin composition containing titanium dioxide and sulfone sulfonate salt | CHEIL INDUSTRIES, INC. (KR) | 2002-08-22 | — | — | US | disclosed |