Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124382 | 0.96 | POLB (0.44) | POLBKDM4EMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL29558643 | 0.96 | POLB (0.44) | POLBKDM4EMAPK1ALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL584753 | 0.85 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2MAPTHSD11B1 | |
| SCHEMBL3952116 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2MAPTHSD11B1 | |
| Potassium Ion SCHEMBL7534241 | 0.82 | CA1 (0.46) | ALDH1A1TSHRHSD11B1MEN1KMT2A | |
| Potassium Ion SCHEMBL3009008 | 0.81 | MCL1 (0.52) | KDM4EMAPK1ALDH1A1LMNATSHR | |
| Potassium Ion SCHEMBL29653831 | 0.81 | MCL1 (0.52) | KDM4EMAPK1ALDH1A1LMNATSHR | |
| SCHEMBL6008968 | 0.81 | POLB (0.46) | POLBKDM4EMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL30534511 | 0.81 | POLB (0.46) | POLBKDM4EMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL251503 | 0.81 | POLB (0.46) | POLBKDM4EMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005843-B2 | Polymer electrolyte composition | UBE INDUSTRIES, LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-8710176-B2 | Method for producing a sulfonated polyarylether block copolymer | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8445141-B2 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2013-05-21 | — | — | US | disclosed |
| EP-2362472-B1 | Production method for polymer electrolyte | UBE INDUSTRIES (JP) | 2012-10-24 | — | — | EP | disclosed |
| EP-2362473-B1 | Producion method for polymer electrolyte | UBE INDUSTRIES (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120264835-A1 | METHOD FOR PRODUCING A SULFONATED POLYARYLETHER BLOCK COPOLYMER | UBE INDUESTIRES, LTD. (JP) | 2012-10-18 | — | — | US | disclosed |
| EP-2355218-B1 | Novel polymer electrolyte, polymer electrolyte composition, electrolyte membrane, and production method and use thereof | UBE INDUSTRIES (JP) | 2012-10-03 | — | — | EP | disclosed |
| US-20120171598-A1 | POLYMER ELECTROLYTE COMPOSITION | UBE INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20120164557-A1 | METHOD FOR PRODUCING A POLYMER ELECTROLYTE MEMBRANE | UBE INDUSTRIES, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-1855339-B1 | NOVEL POLYMER ELECTROLYTE, POLYMER ELECTROLYTE COMPOSITION, ELECTROLYTE MEMBRANE, AND PRODUCTION METHOD AND USE THEREOF | UBE INDUSTRIES (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20100047661-A1 | POLYMER LAMINATE MEMBRANE, THE METHOD FOR PRODUCING THE MEMBRANE AND THE USE OF THE MEMBRANE | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-02-25 | — | — | US | disclosed |
| US-7638220-B2 | Polymeric laminates, processes for producing the same, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090075147-A1 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20080171252-A1 | Novel Polymer Electrolyte, Polymer Electrolyte Composition, Electrolyte Membrane, and Production Method and Use Thereof | UBE INDUSTRIES, LTD. (JP) | 2008-07-17 | — | — | US | disclosed |
| EP-1889863-A1 | SULFONIC ACID GROUP-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION CONTAINING SUCH SULFONIC ACID GROUP-CONTAINING POLYMER, POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE/ELECTRODE ASSEMBLY, AND FUEL CELL | Toyo Boseki Kabushiki Kasisha (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-1855339-A1 | NOVEL POLYMER ELECTROLYTE, POLYMER ELECTROLYTE COMPOSITION, ELECTROLYTE MEMBRANE, AND PRODUCTION METHOD AND USE THEREOF | Ube Industries, Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20060166047-A1 | Polymeric laminates, processes for producing the same, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1519435-A1 | POLYMERIC LAMINATES, PROCESSES FOR PRODUCING THE SAME, AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-03-30 | — | — | EP | disclosed |
| US-6451921-B2 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2002-09-17 | — | — | US | disclosed |
| US-20010021764-A1 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2001-09-13 | — | — | US | disclosed |