Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537015 | 0.84 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2TP53ALDH1A1LMNA | |
| SCHEMBL7537235 | 0.81 | ALDH1A1 (0.53) | POLBMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7539015 | 0.81 | LMNA (0.55) | MAPTSMN1; SMN2TP53LMNAHTT | |
| SCHEMBL7537349 | 0.79 | LMNA (0.53) | MAPTSMN1; SMN2TP53LMNAHPGD | |
| SCHEMBL7533552 | 0.77 | NR1H3 (0.57) | POLBMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11455802 | 0.72 | ALDH1A1 (0.73) | MAPTSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL7533715 | 0.72 | LMNA (0.52) | POLBMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7534437 | 0.72 | KMT2A (0.47) | SMN1; SMN2TP53ALDH1A1LMNAKDM4E | |
| SCHEMBL7531331 | 0.72 | DHODH (0.55) | POLBMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7530855 | 0.72 | KMT2A (0.49) | SMN1; SMN2TP53ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |