Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534822 | 0.86 | HTT (0.51) | MAPTGPR27LMNAACLYMEN1 | |
| SCHEMBL7537385 | 0.84 | ACLY (0.51) | MAPTKDM4EGRM4GPR27LMNA | |
| SCHEMBL7531823 | 0.84 | MAPT (0.55) | MAPTKDM4EGRM4GPR27LMNA | |
| SCHEMBL7531845 | 0.83 | HTT (0.47) | MAPTGRM4GPR27LMNAACLY | |
| SCHEMBL7531372 | 0.83 | SLC10A2 (0.48) | MAPTKDM4EGRM4GPR27ACLY | |
| SCHEMBL7537270 | 0.82 | ITGA1 (0.47) | MAPTKDM4ELMNATP53ACLY | |
| SCHEMBL7531761 | 0.82 | MAPT (0.49) | MAPTKDM4EGRM4GPR27LMNA | |
| SCHEMBL7530740 | 0.81 | MEN1 (0.50) | MAPTKDM4EGRM4GPR27LMNA | |
| SCHEMBL7531893 | 0.81 | HTT (0.50) | MAPTGPR27LMNAACLYMEN1 | |
| SCHEMBL7531850 | 0.79 | ACLY (0.46) | MAPTKDM4EGRM4LMNAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |