Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530687 | 0.88 | HTT (0.48) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7531380 | 0.85 | HTT (0.52) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7533592 | 0.83 | METAP2 (0.46) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7531709 | 0.83 | SLC40A1 (0.65) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7537973 | 0.82 | LMNA (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7531823 | 0.82 | MAPT (0.55) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7537224 | 0.81 | ACLY (0.47) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7531858 | 0.80 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7534407 | 0.80 | LMNA (0.56) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7537945 | 0.80 | HPGD (0.67) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |