Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NRP1 | O14786 | 1/20 | 0.49 |
| ▸ | NPR1 | P16066 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538971 | 0.92 | KMT2A (0.57) | KDM4EMEN1KMT2AMAPTPKM | |
| SCHEMBL7185869 | 0.81 | MAPT (1.00) | KDM4EMEN1KMT2AMAPTPKM | |
| SCHEMBL7531709 | 0.81 | SLC40A1 (0.65) | MEN1KMT2AMAPTALDH1A1ATM | |
| SCHEMBL7531380 | 0.80 | HTT (0.52) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7531707 | 0.79 | RECQL (0.60) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7531823 | 0.78 | MAPT (0.55) | KDM4EMEN1KMT2AMAPTPKM | |
| SCHEMBL7537973 | 0.78 | LMNA (0.46) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7538871 | 0.77 | METAP2 (0.53) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7531858 | 0.76 | KMT2A (0.55) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7533299 | 0.75 | CASP3 (0.61) | MEN1KMT2APKMALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |