Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506619 | 0.90 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2LMNACA1 | |
| SCHEMBL7522811 | 0.85 | LMNA (0.52) | ALDH1A1SMN1; SMN2LMNACA1CA2 | |
| SCHEMBL257480 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7261912 | 0.76 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2KMT2APKM | |
| SCHEMBL7522814 | 0.76 | LMNA (0.51) | ALDH1A1L3MBTL1SMN1; SMN2LMNACA1 | |
| SCHEMBL28849841 | 0.75 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMEP1B | |
| SCHEMBL13917758 | 0.75 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMEP1B | |
| SCHEMBL7345656 | 0.75 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1SMN1; SMN2LMNACA1 | |
| SCHEMBL20743746 | 0.74 | MMP9 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2LMNACA1 | |
| SCHEMBL8285177 | 0.73 | MEP1B (0.62) | ALDH1A1SMN1; SMN2LMNAMEP1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028797-A1 | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028797-A1 | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists | ADRB3, ADRB1, ADRB2 | ALDH1A1 1800/4885L3MBTL1 3246/4885SMN1; SMN2 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.