SCHEMBL754199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16925455	0.81	LMNA (0.42)	ALDH1A1CYP1A2CYP2C9CYP2C19HPGD
	SCHEMBL17922058	0.80	ALDH1A1 (0.44)	ALDH1A1CYP1A2CYP2C9CYP2C19HPGD
	SCHEMBL11775315	0.79	ALDH1A1 (0.44)	ALDH1A1CYP1A2CYP2C9CYP2C19HPGD
	SCHEMBL756756	0.77	RAB9A (0.48)	ALDH1A1HPGDGAAHSD17B10KDM4E
	SCHEMBL17922059	0.74	KMT2A (0.41)	ALDH1A1HPGDGAAHSD17B10KDM4E
	SCHEMBL6268512	0.69	ALDH1A1 (0.43)	ALDH1A1CYP1A2CYP2C19HPGDGAA
	SCHEMBL3444338	0.69	KDM4E (0.49)	ALDH1A1HPGDGAAHSD17B10KDM4E
	SCHEMBL8053715	0.68	CYP1A2 (0.68)	ALDH1A1CYP1A2CYP2C9CYP2C19HPGD
	SCHEMBL11086189	0.67	L3MBTL1 (0.33)	CYP1A2CYP2C19KDM4EKMT2AMEN1
	SCHEMBL11898746	0.67	KDM4E (0.44)	ALDH1A1CYP1A2CYP2C9CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.