Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540486 | 0.70 | SLC27A1 (0.33) | MEN1KMT2ASLC27A1 | |
| SCHEMBL7536844 | 0.70 | SIRT1 (0.38) | ALOX5MEN1KMT2ACXCL12 | |
| SCHEMBL7540660 | 0.69 | ALDH1A1 (0.48) | POLBSLC27A1 | |
| SCHEMBL7601537 | 0.68 | TGFBR1 (0.35) | SLC27A1 | |
| SCHEMBL7542661 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL1842323 | 0.64 | NPC1 (0.52) | ALOX5MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL1844041 | 0.63 | NPC1 (0.51) | ALOX5MEN1POLBKMT2A | |
| SCHEMBL27566816 | 0.61 | NPC1 (0.44) | MEN1KMT2A | |
| SCHEMBL11359838 | 0.60 | ALOX15 (0.39) | MEN1POLBKMT2ASLC27A1 | |
| SCHEMBL340272 | 0.59 | ALDH1A1 (0.70) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |