Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.49 |
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.48 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1350859 | 0.89 | MEN1 (0.54) | ALDH1A1KCNH2RARBHAO1MEN1 | |
| Bicarbonate SCHEMBL20791903 | 0.89 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sulfuric Acid SCHEMBL544764 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL10969631 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL17003947 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL15752866 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL2347222 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL64908 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL17003825 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP | |
| Sulfuric Acid SCHEMBL11618606 | 0.89 | KCNH2 (0.57) | KCNH2MEN1KMT2ACA2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887392-B1 | SILICONE EMULSION COATING COMPOSITION AND PROCESSES FOR THE PREPARATION THEREOF | MATSUSHITA ELECTRIC WORKS LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6025077-A | COATED ARTICLES WITH SILICONE EMULSIONS, POLYSTYRENE, SILICA, EMULSIFIERS AND WATER | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0887392-A1 | SILICONE EMULSION COATING COMPOSITION AND PROCESSES FOR THE PREPARATION THEREOF | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |