SCHEMBL754611

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755609	0.87	LMNA (0.41)	PPARAPPARGPPARDP4HTMLMNA
	SCHEMBL16925408	0.73	LMNA (0.38)	PPARAPPARGPPARDLMNAL3MBTL1
	SCHEMBL8329550	0.73	L3MBTL1 (0.54)	PPARAPPARGPPARDLMNAL3MBTL1
	SCHEMBL16921619	0.72	LMNA (0.41)	PPARAPPARGPPARDP4HTMLMNA
	SCHEMBL755105	0.71	NPSR1 (0.52)	LMNAL3MBTL1ALDH1A1
	SCHEMBL8329553	0.70	L3MBTL1 (0.51)	PPARAPPARGPPARDLMNAL3MBTL1
	SCHEMBL7005190	0.70	LMNA (0.41)	PPARAPPARGPPARDLMNAL3MBTL1
	SCHEMBL13195088	0.69	ALDH1A1 (0.51)	PPARAPPARGPPARDLMNAL3MBTL1
	SCHEMBL226698	0.69	P4HTM (0.69)	PPARGP4HTMLMNAL3MBTL1MMP13
	SCHEMBL753336	0.69	P4HTM (0.53)	P4HTML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.