SCHEMBL755105

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755609	0.78	LMNA (0.41)	NPSR1MAPTL3MBTL1LMNAKDM4E
	SCHEMBL756599	0.77	NPSR1 (0.70)	NPSR1TP53MAPTTHRBL3MBTL1
	SCHEMBL554576	0.74	NPSR1 (0.52)	NPSR1MAPTPOLBLMNAMEN1
	SCHEMBL8329550	0.72	L3MBTL1 (0.54)	MAPTL3MBTL1POLBLMNAMEN1
	SCHEMBL754611	0.71	PPARA (0.47)	L3MBTL1LMNAALDH1A1
	SCHEMBL20050243	0.70	NPSR1 (0.53)	NPSR1POLBLMNAALDH1A1
	SCHEMBL8329553	0.70	L3MBTL1 (0.51)	MAPTL3MBTL1POLBLMNAMEN1
	SCHEMBL7005190	0.69	LMNA (0.41)	L3MBTL1LMNAMEN1ALDH1A1KMT2A
	SCHEMBL13195088	0.69	ALDH1A1 (0.51)	NPSR1MAPTL3MBTL1POLBLMNA
	SCHEMBL9044319	0.68	TSHR (0.40)	NPSR1TP53MAPTL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.