SCHEMBL755609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754611	0.87	PPARA (0.47)	LMNAALDH1A1MMP13L3MBTL1MAOB
	SCHEMBL16925408	0.84	LMNA (0.38)	LMNAKMT2AMAPTMEN1KDM4E
	SCHEMBL16921619	0.84	LMNA (0.41)	LMNAKMT2AMAPTMEN1KDM4E
	SCHEMBL755105	0.78	NPSR1 (0.52)	LMNAKMT2AMAPTMEN1KDM4E
	SCHEMBL27686080	0.76	MAPT (0.49)	LMNAKMT2AMAPTMEN1KDM4E
	SCHEMBL11630338	0.74	GABRA1 (0.52)	LMNAMAPTKDM4EALDH1A1NPSR1
	SCHEMBL8329550	0.74	L3MBTL1 (0.54)	LMNAKMT2AMAPTMEN1ALDH1A1
	Hydrochloric Acid SCHEMBL11631612	0.73	GABRA1 (0.51)	LMNAMAPTKDM4EALDH1A1NPSR1
	SCHEMBL8329553	0.71	L3MBTL1 (0.51)	LMNAKMT2AMAPTMEN1ALDH1A1
	SCHEMBL7005190	0.71	LMNA (0.41)	LMNAKMT2AMEN1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.