SCHEMBL7548705

SCHEMBL7548705

CCOC(=O)n1ccc(=O)[nH]c1=S

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPO P22079 4/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PKM P14618 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
PPARG P37231 1/20 0.39
RAB9A P51151 1/20 0.39
NCOA2 Q15596 1/20 0.39
NCOA1 Q15788 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
BCHE P06276 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
DUT P33316 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26295022 0.76 LPO (0.57) LPOLMNACYP1A2ALDH1A1MAPT
SCHEMBL28446321 0.71 DUT (0.35) LMNACYP1A2PKMALDH1A1DUT
SCHEMBL23007232 0.70 PIN1 (0.40) LPOLMNACYP1A2PKMALDH1A1
SCHEMBL7213480 0.70 PKM (0.46) PKMDUT
SCHEMBL31748519 0.69 LPO (0.45) LPOLMNACYP1A2ALDH1A1MAPT
SCHEMBL24211591 0.69 NAAA (0.38) LMNAALDH1A1MAPTDUT
SCHEMBL6937491 0.69 L3MBTL1 (0.55) LMNAPKMALDH1A1KMT2ADUT
SCHEMBL24211592 0.68 NAAA (0.36) ALDH1A1MAPTDUT
SCHEMBL10511129 0.68 KDM4E (0.50) LPOLMNACYP1A2ALDH1A1MAPT
SCHEMBL11583672 0.68 PKM (0.44) PKMALDH1A1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11092461-A None JP disclosed
EP-0896043-B1 Adhesive TOKUYAMA CORP (JP) 2002-10-23 EP disclosed
EP-0802194-B1 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORP (JP) 2002-06-19 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
JP-H1192461-A DISULFIDE COMPOUND AND METAL SURFACE TREATING AGENT TOKUYAMA CORP 1999-04-06 JP disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5795497-A Thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1998-08-18 US disclosed
EP-0802194-A2 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1997-10-22 EP disclosed