SCHEMBL754937

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL757246	0.84	POLB (0.38)	ALDH1A1POLBPTGER2SMN1; SMN2MAPT
	SCHEMBL752919	0.82	POLB (0.37)	ALDH1A1POLBNPSR1MAPTLMNA
	SCHEMBL10290778	0.81	ALDH1A1 (0.36)	ALDH1A1POLBALOX12PTGER2SMN1; SMN2
	SCHEMBL755830	0.76	MAPT (0.43)	ALDH1A1POLBALOX15KDM4ENPC1
	SCHEMBL755341	0.76	MMP1 (0.40)	ALDH1A1POLBKDM4ENPSR1MAPT
	SCHEMBL755271	0.72	PTGER1 (0.38)	ALDH1A1POLBSMN1; SMN2HPGDNPC1
	SCHEMBL753088	0.71	POLB (0.38)	ALDH1A1POLBNPSR1MAPTLMNA
	SCHEMBL755559	0.71	MMP3 (0.47)	ALDH1A1POLBSMN1; SMN2KDM4EHPGD
	SCHEMBL755446	0.71	TEAD4 (0.42)	ALDH1A1POLBKDM4EGAAMAPT
	Aniline SCHEMBL752234	0.70	ALDH1A1 (0.38)	ALDH1A1POLBKDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.