Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572878 | 0.86 | ALDH1A1 (0.47) | ALDH1A1FKBP1AMEN1KMT2ACHRM5 | |
| SCHEMBL7505846 | 0.81 | ALDH1A1 (0.49) | ALDH1A1FKBP1AKMT2APKMMMP1 | |
| SCHEMBL7552475 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2APKMNPSR1MMP1 | |
| SCHEMBL7515028 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2APKMNPSR1MMP1 | |
| SCHEMBL7549978 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APKMMMP1 | |
| SCHEMBL7505933 | 0.76 | LTA4H (0.47) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL7550598 | 0.76 | ALDH1A1 (0.52) | ALDH1A1FKBP1AKMT2APKMMMP1 | |
| SCHEMBL7509731 | 0.75 | MMP13 (0.47) | ALDH1A1FKBP1AKMT2APKMMMP1 | |
| SCHEMBL7510199 | 0.75 | KCNH2 (0.51) | FKBP1AMEN1KMT2ACHRM5MMP1 | |
| SCHEMBL7510863 | 0.75 | POLB (0.54) | MEN1KMT2APKMNPSR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | ALDH1A1 3024/4885FKBP1A 2409/4885MEN1 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.