Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005350 | 0.85 | SLC6A5 (0.38) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7564220 | 0.84 | MAPT (0.38) | MAPTHSD17B2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7007505 | 0.76 | SLC6A5 (0.37) | ALDH1A1KDM4EKMT2AGAATSHR | |
| SCHEMBL7004077 | 0.74 | SLC6A5 (0.38) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7556806 | 0.72 | BAZ2B (0.38) | MAPTALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL7007295 | 0.72 | PTPN11 (0.37) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL7007699 | 0.70 | CRHBP (0.39) | MAPTALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL7561375 | 0.69 | TDP1 (0.42) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7559797 | 0.69 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL15005381 | 0.67 | ALDH1A1 (0.57) | MAPTHSD17B2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |