Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | CISD2 | Q8N5K1 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561599 | 0.83 | MAPT (0.52) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL7561597 | 0.71 | GPR27 (0.54) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL3595563 | 0.70 | L3MBTL1 (0.77) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL7533623 | 0.68 | ACLY (0.55) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL3990264 | 0.67 | KMT2A (0.67) | L3MBTL1MAPTNPC1RAB9ALMNA | |
| SCHEMBL7532801 | 0.67 | FADS1 (0.59) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL3794687 | 0.66 | NPC1 (1.00) | MAPTNPC1RAB9ALMNAADORA1 | |
| SCHEMBL3595560 | 0.66 | L3MBTL1 (0.73) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL20838917 | 0.66 | CISD2 (0.84) | MAPTNPC1RAB9AGAACISD2 | |
| SCHEMBL1884170 | 0.66 | MEN1 (0.74) | MAPTNPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |