SCHEMBL7563589

SCHEMBL7563589

CC(=O)C(=O)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.56
CYP2C9 P11712 2/20 0.56
HPGD P15428 2/20 0.55
GAA P10253 1/20 0.55
PTPN1 P18031 1/20 0.54
CYP2D6 P10635 2/20 0.53
CYP2C19 P33261 2/20 0.53
CYP1A2 P05177 1/20 0.53
TSHR P16473 1/20 0.53
RIPK1 Q13546 1/20 0.53
ALOX12 P18054 1/20 0.52
EPHX1 P07099 1/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16349729 0.87 GAA (0.56) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL3056874 0.87 KMT2A (0.71) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL8525398 0.84 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL183463 0.84 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL13130712 0.84 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL97001 0.83 KMT2A (0.68) ALDH1A1KMT2AMEN1MAPTSMN1; SMN2
SCHEMBL1867492 0.83 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL20438786 0.82 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL10058715 0.82 MEN1 (0.66) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL4486771 0.82 KMT2A (0.66) ALDH1A1KMT2AMEN1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056724-A1 IMINOAMIDE-TYPE COMPOUNDS AS LIGANDS FOR COPPER-CATALYZED COUPLING REACTIONS OF (HETERO)ARYL HALIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-03-20 WO disclosed
US-20230348365-A1 COMPOUNDS FOR TREATING INFECTIONS ARTS & CIÈNCIES EUROPA (AD) 2023-11-02 US disclosed
WO-2023109926-A1 SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG 南京药石科技股份有限公司 2023-06-22 WO disclosed
WO-2021252644-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-12-16 WO disclosed
US-8426359-B2 Inhibitors of serine proteases, particularly HCV NS3-NS4A protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-04-23 US disclosed
US-8314141-B2 Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-11-20 US disclosed
US-8314141-B2 Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-11-20 US disclosed
EP-2314598-A1 Inhibitors of Hepatitis C virus NS3 serine protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-04-27 EP disclosed
US-20110059018-A1 COVALENTLY BINDING IMAGING PROBES SANOFI-AVENTIS (FR) 2011-03-10 US disclosed
US-7605264-B2 Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2009-10-20 US disclosed
US-20070270453-A1 TRICYCLIC MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF BRISTOL-MYERS SQUIBB COMPANY 2007-11-22 US disclosed
US-20070270453-A1 TRICYCLIC MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF BRISTOL-MYERS SQUIBB COMPANY 2007-11-22 US disclosed
US-7253283-B2 Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2007-08-07 US disclosed
US-7253283-B2 Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2007-08-07 US disclosed
EP-1206241-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
WO-2001013882-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO disclosed
US-5364617-A Protection from solar radiation, chelate with iron in body and reduce its ability to catalyze formation of oxygen free radicals THE PROCTER & GAMBLE COMPANY (US) 1994-11-15 US disclosed
EP-0611301-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1994-08-24 EP disclosed
EP-0611301-A4 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS. PROCTER & GAMBLE (US) 1993-03-01 EP disclosed
WO-1991016034-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348365-A1 COMPOUNDS FOR TREATING INFECTIONS DPM1, TREH, MPO ALDH1A1 262/4885KMT2A 1543/4885MEN1 600/4885
US-20110059018-A1 COVALENTLY BINDING IMAGING PROBES CTSV, CTSL, CTSE ALDH1A1 1016/4885KMT2A 3834/4885MEN1 1935/4885
US-20070270453-A1 TRICYCLIC MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF NFRKB, NFKBIA, NFKB1 ALDH1A1 3536/4885KMT2A 3366/4885MEN1 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.