Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169622 | 0.88 | CTSK (0.45) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7241696 | 0.82 | CTSK (0.41) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7163876 | 0.74 | HTR6 (0.43) | KMT2AALDH1A1POLBALOX15PPARG | |
| SCHEMBL7167328 | 0.71 | CTSK (0.56) | KMT2AMEN1SMN1; SMN2POLBPPARG | |
| SCHEMBL14313616 | 0.69 | ALOX15 (0.74) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL5099014 | 0.68 | NTSR1 (0.58) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL5098994 | 0.68 | NTSR1 (0.58) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL3137759 | 0.68 | PPARG (0.63) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL9239543 | 0.68 | ALOX15 (0.71) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL18019186 | 0.68 | LARS1 (0.55) | ALDH1A1POLBPPARGSLC40A1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | CTSK, CTSZ, CTSG | KMT2A 2970/4885ALDH1A1 3948/4885KDM4E 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.