Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567197 | 0.86 | KDM4E (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7567204 | 0.84 | NPC1 (0.47) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7570655 | 0.79 | AOX1 (0.45) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL7572166 | 0.79 | AOX1 (0.45) | KDM4EALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7573613 | 0.78 | TAS1R3 (0.54) | HPGDSMN1; SMN2TAS1R3TAS1R1PARP1 | |
| SCHEMBL7564805 | 0.78 | KDM4E (0.49) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7567392 | 0.77 | CTSS (0.45) | POLBSMN1; SMN2TAS1R3TAS1R1PARP1 | |
| SCHEMBL7571848 | 0.76 | AOX1 (0.52) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7568147 | 0.76 | KDM4E (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7564799 | 0.75 | HDAC1 (0.52) | KDM4EALDH1A1HPGDGLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |