SCHEMBL756505

SCHEMBL756505

Oc1ccc(C(c2ccc(O)cc2)(C(F)(F)Cl)C(F)(F)Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.65
ESR2 Q92731 10/20 0.65
KIF11 P52732 1/20 0.50
CYP3A4 P08684 3/20 0.44
LMNA P02545 2/20 0.44
TYR P14679 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
AR P10275 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10552537 0.91 ESR1 (0.74) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL756504 0.81 ESR1 (0.74) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL8067180 0.79 ESR1 (0.78) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL4560440 0.79 ESR1 (1.00) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL134173 0.79 ESR1 (0.56) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL9790796 0.79 ESR1 (0.56) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL3686864 0.79 ESR1 (1.00) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL9790808 0.79 ESR1 (0.56) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL21027 0.79 ESR1 (1.00) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL7738788 0.78 ESR1 (0.46) ESR1ESR2KIF11CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4196255-A EPICHLOROHYDRIN ELASTOMER, DIVALENT METAL OXIDE OR HYDROXIDE, FLUOROPOLYOL, BASIC NITROGEN OR PHOSPHORUS COMPOUND DAIKIN KOGYO CO., LTD. (JP) 1980-04-01 US claimed
US-4141874-A Fluorine-containing elastomeric copolymers, process for preparing the same and composition containing the same DAIKIN KOGYO CO., LTD. (JP) 1979-02-27 US claimed
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME DAIKIN INDUSTRIES, LTD. (JP) 2026-05-21 US disclosed
US-12590653-B2 Fuel hose SUMITOMO RIKO COMPANY LIMITED (JP) 2026-03-31 US disclosed
EP-2804905-B1 FLUORORUBBER COMPOSITION DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
EP-4001322-B1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER, AND COMPOSITION DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
US-12473386-B2 Fluorine-containing elastomer, crosslinkable composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2025-11-18 US disclosed
EP-4600300-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2025-08-13 EP disclosed
EP-4563645-A1 CROSSLINKABLE COMPOSITION AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-06-04 EP disclosed
EP-4563646-A1 CROSSLINKABLE COMPOSITION AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-06-04 EP disclosed
US-20250171613-A1 CROSSLINKABLE COMPOSITION AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
EP-0067853-A4 FLAME RETARDANT AROMATIC POLYCARBONATES MADE FROM FLUORINATED DIPHENOLS. GEN ELECTRIC (US) 1983-04-06 EP disclosed
EP-0067853-A1 FLAME RETARDANT AROMATIC POLYCARBONATES MADE FROM FLUORINATED DIPHENOLS. GEN ELECTRIC (US) 1982-12-29 EP disclosed
WO-1982002402-A1 FLAME RETARDANT AROMATIC POLYCARBONATE COMPOSITIONS MADE FROM FLUORINATED DIPHENOLS GEN ELECTRIC (US) 1982-07-22 WO disclosed
EP-0004087-B1 EPICHLORHYDRIN POLYMER ELASTOMERIC COMPOSITION AND LAYERED PRODUCTS COMPRISING A LAYER OBTAINED FROM SAID COMPOSITION AND A FLUOROELASTOMER LAYER Daikin Kogyo Co., Ltd. (JP) 1981-01-28 EP disclosed
US-4196255-A EPICHLOROHYDRIN ELASTOMER, DIVALENT METAL OXIDE OR HYDROXIDE, FLUOROPOLYOL, BASIC NITROGEN OR PHOSPHORUS COMPOUND DAIKIN KOGYO CO., LTD. (JP) 1980-04-01 US disclosed
EP-0004087-A1 Epichlorhydrin polymer elastomeric composition and layered products comprising a layer obtained from said composition and a fluoroelastomer layer Daikin Kogyo Co., Ltd. (JP) 1979-09-19 EP disclosed
US-4141874-A Fluorine-containing elastomeric copolymers, process for preparing the same and composition containing the same DAIKIN KOGYO CO., LTD. (JP) 1979-02-27 US disclosed
US-3951913-A QUATERNARY AMMONIUM 8-ALKYL- OR ARALKYL-1,8-DIAZA-BICYCLO(5.4.0)-7-UNDECENIUM DAIKIN KOGYO CO., LTD. (JA) 1976-04-20 US disclosed
US-3931129-A FLUOROELASTOMER COMPOSITION DAIKIN KOGYO CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590653-B2 Fuel hose HAO2, HOGA1, FGB ESR1 1781/4885ESR2 1723/4885KIF11 1560/4885
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME PFN1, RAD54L, FGB ESR1 934/4885ESR2 1551/4885KIF11 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.