SCHEMBL756752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756649	0.86	KMO (0.47)	KMOCYTH2CYP2C19ALDH1A1KDM4E
	SCHEMBL752750	0.73	NPC1 (0.50)	CYP2C19ALDH1A1SMN1; SMN2
	SCHEMBL3434693	0.69	KDM4E (0.58)	KMOCYTH2CYP2C19ALDH1A1KDM4E
	SCHEMBL14758742	0.66	KMO (1.00)	KMOCYP2C19PIK3CAPOLBSLC40A1
	SCHEMBL8055002	0.66	KMO (0.52)	KMOCYP2C19ALDH1A1KDM4EHPGD
	SCHEMBL31633227	0.66	CYP2C19 (0.75)	KMOCYP2C19ALDH1A1KDM4EPOLB
	SCHEMBL2178561	0.65	KMO (0.62)	KMOCYP2C19ALDH1A1KDM4ELMNA
	SCHEMBL14742216	0.64	KMO (0.80)	KMOCYP2C19ALDH1A1KDM4EPOLB
	SCHEMBL753011	0.63	JAK2 (0.45)	KDM4EPOLBLMNA
	SCHEMBL25559898	0.63	KIT (0.53)	KMOCYP2C19ALDH1A1KDM4EPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.