SCHEMBL756649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756752	0.86	KMO (0.49)	KMOCYTH2ALDH1A1HTTHSD17B10
	SCHEMBL3434693	0.67	KDM4E (0.58)	KMOCYTH2ALDH1A1HTTHSD17B10
	SCHEMBL754568	0.65	ACACB (0.40)	ALDH1A1HTTKDM4EHPGDSMN1; SMN2
	SCHEMBL754532	0.65	JAK2 (0.43)	KDM4EPOLBLMNATSHR
	SCHEMBL14758742	0.64	KMO (1.00)	KMOCYP2C19GAAPOLBSLC40A1
	SCHEMBL755666	0.64	P2RX3 (0.35)	HSD17B10POLBSMN1; SMN2USP2TSHR
	SCHEMBL31633227	0.64	CYP2C19 (0.75)	KMOALDH1A1HTTCYP2C19GAA
	SCHEMBL8055002	0.64	KMO (0.52)	KMOALDH1A1HTTHSD17B10CYP2C19
	SCHEMBL2178561	0.63	KMO (0.62)	KMOALDH1A1CYP2C19KDM4ESMN1; SMN2
	SCHEMBL14742216	0.62	KMO (0.80)	KMOALDH1A1CYP2C19GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.