Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 8/20 | 0.56 |
| ▸ | BRD1 | O95696 | 1/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | BRD2 | P25440 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590368 | 0.84 | ACLY (0.58) | SLC22A12BRD4SMN1; SMN2ALDH1A1ACLY | |
| SCHEMBL7364604 | 0.80 | CA12 (0.59) | SLC22A12PKMBRD4PTPN2PTPN1 | |
| SCHEMBL22034239 | 0.80 | SLC22A12 (0.55) | SLC22A12PKMBRD4MEN1KMT2A | |
| SCHEMBL5305683 | 0.79 | LMNA (0.66) | SLC22A12PKMBRD4PTPN2PTPN1 | |
| SCHEMBL95649 | 0.78 | SLC22A12 (0.55) | SLC22A12PKMBRD4BRD1BRPF1 | |
| SCHEMBL28504349 | 0.77 | HTR6 (0.57) | SLC22A12PKMBRD4BRD1BRPF1 | |
| SCHEMBL7573915 | 0.77 | LMNA (0.78) | PKMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28806365 | 0.77 | SMN1; SMN2 (0.73) | SLC22A12PKMBRD4MEN1KMT2A | |
| SCHEMBL13615295 | 0.77 | ALDH1A1 (0.57) | SLC22A12PKMBRD4BRD1BRPF1 | |
| SCHEMBL13629773 | 0.77 | ALDH1A1 (0.57) | SLC22A12PKMBRD4BRD1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |