Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569855 | 0.84 | SLC22A12 (0.58) | ACLYBRD4ALDH1A1SLC22A12SMN1; SMN2 | |
| SCHEMBL12393189 | 0.78 | ACLY (0.58) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL23014188 | 0.78 | ALDH1A1 (0.71) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL7364604 | 0.77 | CA12 (0.59) | ACLYBRD4ALDH1A1SLC22A12SMN1; SMN2 | |
| SCHEMBL31612009 | 0.77 | SLC40A1 (0.56) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL27908886 | 0.77 | TSHR (0.69) | ACLYTSHRNPC1ALDH1A1MAPT | |
| SCHEMBL28146309 | 0.76 | HTR6 (0.55) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL29782232 | 0.76 | SLC40A1 (0.66) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL13852850 | 0.76 | BRD4 (0.56) | ACLYTSHRNPC1SLC40A1BRD4 | |
| SCHEMBL7594059 | 0.76 | CCR2 (0.55) | ACLYTSHRALDH1A1MAPTSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |