SCHEMBL9865680

SCHEMBL9865680

O=CCN=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.48
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 2/20 0.44
CYP2A6 P11509 1/20 0.44
CA1 P00915 3/20 0.42
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
G6PC1 P35575 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
NOX1 Q9Y5S8 1/20 0.39
TRPA1 O75762 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12894229 1.00 CA2 (0.48) CA2LMNAL3MBTL1ALDH1A1CYP2A6
SCHEMBL14138210 0.88 ALDH1A1 (0.39) CA2ALDH1A1CA1CA12CA9
SCHEMBL7571738 0.77 LMNA (0.48) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL7603166 0.77 LMNA (0.48) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL6888679 0.77 LMNA (0.48) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL8141068 0.77 LMNA (0.48) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL8924551 0.76 L3MBTL1 (0.46) CA2LMNAL3MBTL1G6PC1GRIN1
SCHEMBL845362 0.75 CA2 (0.61) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL845363 0.75 CA2 (0.61) CA2LMNAL3MBTL1ALDH1A1CA1
SCHEMBL19958893 0.75 LMNA (0.57) CA2LMNAL3MBTL1ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5032606-A Novel fluorinated resorcinol ethers and their use as anti-allergics and anti-inflammatories CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4863942-A Novel resorcinol ethers and anti-inflammatory and anti-allergic use thereof CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
US-4820726-A Oxaloamino substituted fluorinated resorcinol ethers and anti-allergic and anti-inflammatory use thereof CIBA-GEIGY CORPORATION (US) 1989-04-11 US disclosed
US-4670604-A Novel fluorinated resorcinol ethers CIBA-GEIGY CORPORATION (US) 1987-06-02 US disclosed